{"id":1386,"date":"2018-07-25T22:00:00","date_gmt":"2018-07-25T20:00:00","guid":{"rendered":"https:\/\/new.rjl-microanalytic.de\/?p=1386"},"modified":"2023-06-04T15:26:03","modified_gmt":"2023-06-04T13:26:03","slug":"analyse-von-fremdpartikeln-in-pharmazeutischen-pulvern","status":"publish","type":"post","link":"https:\/\/www.rjl-microanalytic.de\/en\/analyse-von-fremdpartikeln-in-pharmazeutischen-pulvern\/","title":{"rendered":"Analysis of Foreign Particles in Pharmaceutical Powders"},"content":{"rendered":"
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Avoiding the presence of visible foreign particles is a core requirement in the manufacturing of pharmaceutical products. Our test laboratory has developed a simple but innovative method that enables the reliable quantification of foreign particles in pharmaceutical powders.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Preparation by Dispersion in Air<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Our preferential method of preparation for flowable powders is via the means of a dispersion tube onto a large CN membrane (\u2205 150 mm). Following this technique, it is possible to examine ca. 100 mg of powder in a single step, increasing the statistical significance of the measurement.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Preparation by Vacuum Filtration<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Alternatively, the primary powder can be dissolved with a suitable solvent and the residue filtered onto a medium sized CN membrane (\u2205 47 mm). This method assumes that the foreign particles are insolvable. The technique is particularly suitable for the investigation of metallic and mineral foreign particles (\"elemental impurities\").<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Analysis Method for Foreign Particles<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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We utilize an optical measuring method based on an\u00a0imaging scanner,<\/a>\u00a0in order to quickly and reliably detect all visible foreign particles. The measurement result is available in two minutes:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\"tabelle-fremdpartikel-pro-100mg\"\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Alternatively, we offer the analysis of\u00a0foreign particles using SEM-EDX.<\/a>\u00a0This method can detect the foreign particles while simultaneously typing the material.<\/p>

Talk to our\u00a0experts<\/a>\u00a0and benefit from our many years of experience.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

A central requirement in the production of pharmaceutical products is the avoidance of visible foreign particles. Our testing laboratory has developed innovative yet simple methods to reliably quantify foreign particles in pharmaceutical powders.<\/p>","protected":false},"author":1,"featured_media":2000,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9,11],"tags":[69,14,70,22,24,32,68,52,38,39,41,43,44,45,49,50,51],"class_list":["post-1386","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-innovative-analytik","category-analyse-technische-sauberkeit","tag-analysen-mit-akkreditierung","tag-bauteilsauberkeit","tag-fremdpartikel","tag-iso-16232","tag-medizinprodukt","tag-partikelanalyse","tag-prueflabor","tag-reinheit","tag-restschmutz","tag-restschmutzanalyse","tag-roentgenelementanalyse","tag-sauberkeitsanalyse","tag-sauberkeitspruefung","tag-sem-edx","tag-technische-sauberkeit","tag-vda-19","tag-vdi-2083-blatt-21"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.rjl-microanalytic.de\/en\/wp-json\/wp\/v2\/posts\/1386","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rjl-microanalytic.de\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rjl-microanalytic.de\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rjl-microanalytic.de\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rjl-microanalytic.de\/en\/wp-json\/wp\/v2\/comments?post=1386"}],"version-history":[{"count":37,"href":"https:\/\/www.rjl-microanalytic.de\/en\/wp-json\/wp\/v2\/posts\/1386\/revisions"}],"predecessor-version":[{"id":10339,"href":"https:\/\/www.rjl-microanalytic.de\/en\/wp-json\/wp\/v2\/posts\/1386\/revisions\/10339"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rjl-microanalytic.de\/en\/wp-json\/wp\/v2\/media\/2000"}],"wp:attachment":[{"href":"https:\/\/www.rjl-microanalytic.de\/en\/wp-json\/wp\/v2\/media?parent=1386"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rjl-microanalytic.de\/en\/wp-json\/wp\/v2\/categories?post=1386"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rjl-microanalytic.de\/en\/wp-json\/wp\/v2\/tags?post=1386"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}